Sarcopenia is characterized by reduced muscle strength and mass and a decline in muscle fiber diameter and amount of sarcomeric proteins.Sarcopenia involves the activation of the ubiquitin-proteasome system (UPS).MuRF-1 and atrogin-1 are Bottle Lamp Couple Card E3 ubiquitin ligases belonging to UPS, leading to proteolysis mediated by the PSMB 5, 6,
Krabbe disease (Kd) is a lysosomal storage disorder (LSD) caused by the deficiency of the lysosomal galactosylceramidase (GALC) which cleaves the myelin enriched lipid galactosylceramide (GalCer).Accumulated GalCer is catabolized into the cytotoxic lipid psychosine that causes myelinating cells death and demyelination which recruits microglia/macro
Time-distributed optical feedback in semiconductor lasers has gained attention for its ability to produce high-quality chaos and effectively suppress the time delay signature.However, the fundamental impact of the distribution of feedback in time on laser dynamics remains unexplored.In this paper, we investigate this topic by using fiber Bragg grat
Hemoperfusion is one of the most important therapies for progressive chronic kidney disease (CKD) and is effective at removing toxins from the blood.Increasing the efficiency of adsorbents applied Huperzine (Huperzin) in hemoperfusion is crucial.In the present study, shell of areca nut, one of the most common waste Chinese herb medicine residue wit
Redox additives have been widely used in various electrolytes to achieve an increase in the energy density of hybrid capacitors.This study investigates the trade-off mechanism of energy density and Inkjet cycle stability for electrochemical capacitors with redox additives.To do so, a 1-dimensional electrochemical model considering both electric dou